Unlocking the Power of Abbokinase: Dissolving Blood Clots with Urokinase Injection


What is Abbokinase?

Abbokinase, also known as Urokinase injection, is primarily used to dissolve blood clots that have formed in the lungs (pulmonary embolism).

Previously, this medicine was only available with a prescription from your doctor.

As of October 2010, Abbokinase is not available in the United States.


In the U.S., Abbokinase is the brand name for the drug Tissue Plasminogen Activator.

Another brand name for Tissue Plasminogen Activator in the U.S. is Kinlytic.


Abbokinase medication contains urokinase that may cause bleeding that is usually not serious but can be severe in certain individuals.

To avoid extreme bleeding, it is critical to follow the guidelines given by your doctor. Limit your movements and only get out of bed when instructed by your doctor.

Check for any signs of bleeding or oozing on the skin where injection was administered or blood was drawn from your arm. Also, pay attention to any presence of blood in urine or during bowel movement.

If you experience any injuries or unusual bleeding while on Abbokinase treatment, contact your doctor, nurse, or healthcare professional immediately.

Prior to Medication Use

Before taking Abbokinase, it is important to weigh the risks and benefits of the medicine.

To make sure this medicine is safe for you, inform your doctor of any allergies you may have towards any medicines, foods, preservatives or animals.

The safety and efficacy of urokinase injection has not been established in pediatric population. No information is available on the relationship between age and geriatric patients.

If you're breastfeeding, evaluate potential benefits against potential risk before taking this medication.

It is important for your healthcare professional to know if you are taking other medicines as some interactions could occur. Your dose might need to be changed or other precautions may be necessary.

Defibrotide should be used with caution while taking certain medicines like Acenocoumarol or Warfarin. In some cases both might be required but consultation from a doctor should be taken first

It's essential that you tell your doctor about any other medical conditions such as bleeding problems (or history), blood vessel problems (e.g., aneurysm), brain disease/tumour/hypertension/uncontrolled/stroke/recent surgery/spine injury/trauma/CPR which can affect its use.

Furthermore, if there are existing blood clotting disorders/diabetic eye complications/injections into a blood vessel/kidney or liver disease/placement of any tube into body/surgery/injury/high cholesterol-it's imperative to consider that there may be an increased chance for serious side effects.

Possible Reactions

Along with its needed effects, Abbokinase may cause some unwanted side effects. Although not all of these side effects may occur, it is important to seek medical attention if they do.

More common side effects include bleeding gums, coughing up blood, difficulty breathing or swallowing, dizziness, headache, increased menstrual flow or vaginal bleeding, nosebleeds, paralysis and prolonged bleeding from cuts. In addition to this are red or black tarry stools and red or dark brown urine. Shortness of breath is also considered a more common side effect.

Rare occurrences have been noted for several other symptoms such as coughs with fast heartbeat hives or welts. You might experience puffiness around the eyes face lips or tongue sometimes accompanied by itching skin alongside noisy breathing and tightness in the chest. Other rare symptoms noted include skin rash unexpected tiredness weakness wheezing along with further complications if not treated properly.

"Incidence not known" refers to symptoms that can develop due to unobserved allergic reactions including but not limited to blue lips and fingernails blurred vision chest pain convulsions coughing that sometimes produces a pink frothy sputum difficult fast or noisy breathing fainting fast irregular pounding racing heartbeat pulse numbness tingling in the face arms legs pale skin severe sudden headache minor speech difficulties swelling in the legs ankles trouble with walking speaking unconsciousness among others.

If you notice any other effects while taking Abbokinase apart from what was listed above check with your healthcare professional as soon as possible.

Recommended Dosage Guidelines

The drug Abbokinase contains urokinase which requires specific instructions on its proper use.

It is important to seek guidance from a trained health professional like a doctor before taking Abbokinase.

This medicine is given through an intravenous injection. The healthcare provider will insert a needle into one of your veins and administer the drug.

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